Poly(lactic acid)-Based Electrospun Fibrous Structures for Biomedical Applications

Poly(lactic acid)(PLA) is an aliphatic polyester that can be derived from natural and renewable resources. Owing to favorable features, such as biocompatibility, biodegradability, good thermal mechanical performance, processability, PLA has been considered one of the most promising biopolymers for biomedical applications. Particularly, electrospun nanofibers with distinguishing characteristics, similarity extracellular matrix, large specific surface area high porosity small pore size tunable properties diverse applications, have recently given rise advanced spillovers in medical area. A variety PLA-based nanofibrous structures explored purposes, wound dressing, drug delivery systems, tissue engineering scaffolds. This review highlights recent advances electrospinning It also gives a comprehensive discussion about approaches suggested optimizing towards design devices appropriate physical, biological functions.